Mount Sinai scientists take novel approach to restore the microbiome of C-section newborns

Scientists from the Icahn Institute for Genomics and Multiscale Biology at the Icahn School of Medicine at Mount Sinai, collaborating with NYU Langone Medical Center and a multi-center team of researchers, demonstrated for the first time that the microbiome of newborn babies delivered via cesarean section (C-section) can be partially restored to resemble that of vaginally delivered infants. By swabbing newborns with a gauze containing vaginal fluids from their mothers, and later testing samples collected from these newborns and their mothers using state-of-the-art genomic technology and computational methods, the research team showed that C-section infants became enriched in vaginal bacteria such as Lactobacillus, which were nearly absent in untreated infants. The team published its findings today in the journal Nature Medicine.

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